Editorial: Second-generation sequencing
نویسندگان
چکیده
منابع مشابه
Exploring the Switchgrass Transcriptome Using Second-Generation Sequencing Technology
BACKGROUND Switchgrass (Panicum virgatum L.) is a C4 perennial grass and widely popular as an important bioenergy crop. To accelerate the pace of developing high yielding switchgrass cultivars adapted to diverse environmental niches, the generation of genomic resources for this plant is necessary. The large genome size and polyploid nature of switchgrass makes whole genome sequencing a daunting...
متن کاملAssembly of large genomes using second-generation sequencing.
Second-generation sequencing technology can now be used to sequence an entire human genome in a matter of days and at low cost. Sequence read lengths, initially very short, have rapidly increased since the technology first appeared, and we now are seeing a growing number of efforts to sequence large genomes de novo from these short reads. In this Perspective, we describe the issues associated w...
متن کاملSecond-generation sequencing for gene discovery in the Brassicaceae.
The Brassicaceae contains the most diverse collection of agriculturally important crop species of all plant families. Yet, this is one of the few families that do not form functional symbiotic associations with mycorrhizal fungi in the soil for improved nutrient acquisition. The genes involved in this symbiosis were more recently recruited by legumes for symbiotic association with nitrogen-fixi...
متن کاملApplication of second-generation sequencing to cancer genomics
New generations of DNA sequencing technologies are enabling the systematic study of genetic derangement in cancers. Sequencing of cancer exomes or transcriptomes or even entire cancer genomes are now possible, though technical and economic challenges remain. Cancer samples are inherently heterogeneous and are often contaminated with normal DNA, placing additional demands on informatics tools fo...
متن کاملHop-variety Identification Using First- and Second- generation Sequencing
Twenty-one hop varieties from Europe and the United States were successfully identified by DNA analysis, based on single nucleotide polymorphisms (SNPs; including insertion/ deletion sequences) as identification markers. Several dozen megabases of transcriptome sequencing data were obtained by next-generation sequencing of samples from three hop varieties and compared to search for the regions ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2010
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbq066